- NOdalol( CORGARD)
DOSAGE MUST BE INDIVIDUALIZED. CORGARD (NADOLOL) MAY BE ADMINISTERED WITHOUT REGARD TO MEALS.Angina Pectoris
The usual initial dose is 40 mg CORGARD (nadolol) once daily. Dosage may be gradually increased in 40 to 80 mg increments at 3 to 7 day intervals until optimum clinical response is obtained or there is pronounced slowing of the heart rate. The usual maintenance dose is 40 or 80 mg administered once daily. Doses up to 160 or 240 mg administered once daily may be needed.The usefulness and safety in angina pectoris of dosage exceeding 240 mg per day have not been established. If treatment is to be discontinued, reduce the dosage gradually over a period of one to two weeks (see WARNINGS).Hypertension
The usual initial dose is 40 mg CORGARD (nadolol) once daily, whether it is used alone or in addition to diuretic therapy. Dosage may be gradually increased in 40 to 80 mg increments until optimum blood pressure reduction is achieved. The usual maintenance dose is 40 or 80 mg administered once daily. Doses up to 240 or 320 mg administered once daily may be needed.
DOSAGE MUST BE INDIVIDUALIZED. CORGARD (NADOLOL) MAY BE ADMINISTERED WITHOUT REGARD TO MEALS.
Angina Pectoris
The usual initial dose is 40 mg CORGARD (nadolol) once daily. Dosage may be gradually increased in 40 to 80 mg increments at 3 to 7 day intervals until optimum clinical response is obtained or there is pronounced slowing of the heart rate. The usual maintenance dose is 40 or 80 mg administered once daily. Doses up to 160 or 240 mg administered once daily may be needed.
The usefulness and safety in angina pectoris of dosage exceeding 240 mg per day have not been established. If treatment is to be discontinued, reduce the dosage gradually over a period of one to two weeks (see WARNINGS).
Hypertension
The usual initial dose is 40 mg CORGARD (nadolol) once daily, whether it is used alone or in addition to diuretic therapy. Dosage may be gradually increased in 40 to 80 mg increments until optimum blood pressure reduction is achieved. The usual maintenance dose is 40 or 80 mg administered once daily. Doses up to 240 or 320 mg administered once daily may be needed.
Atenolol Dose for High Blood Pressure
The recommended starting dosage of atenolol for people with high blood pressure (hypertension) is 50 mg once a day. After a couple of weeks, based on the blood pressure response and/or atenolol side effects, the dosage may be increased or decreased. Your healthcare provider may also add a diuretic (which is a "water pill") or another blood pressure medication if your blood pressure is not controlled by atenolol alone.
The maximum recommended daily atenolol dose for high blood pressure treatment is 100 mg. Higher doses are not likely to be any more effective.
Atenolol Dosage for Angina
is atenolol 50 mg, taken once a day. After one week, based on the response and/or side effects, your healthcare provider may increase or decrease your dosage.
The maximum daily dose for treating angina symptoms is atenolol 200 mg.
3. captopril (Capoten®)
3. captopril (Capoten®)
Captopril Dosing for High Blood Pressure
The recommended starting dosage of captopril for most people with high blood pressure (hypertension) is 25 mg, either two or three times a day. Based on the blood pressure response and/or side effects of captopril, the dosage may be increased or decreased. With each change in dosage, it may take several weeks to see the full effects of captopril on lowering blood pressure.
The recommended starting dosage of captopril for people withcongestive heart failure is 25 mg three times a day. Based on the response and/or side effects, the dosage may be increased or decreased. Most people take an average of 50 mg to 100 mg of captopril three times a day.
The recommended dose of captopril for diabetic nephropathy is 25 mg three times a day.
4. lisinopril (Zestril®)
4. lisinopril (Zestril®)
Usual Adult Dose for Hypertension
Initial dose: 10 mg orally once a day, in patients not receiving a diuretic.
Maintenance dose: 20 to 40 mg orally once a day.
Some patients appear to have a further response to 80 mg, but experience with this dose is limited.
Maintenance dose: 20 to 40 mg orally once a day.
Some patients appear to have a further response to 80 mg, but experience with this dose is limited.
Usual Adult Dose for Congestive Heart Failure
Initial dose: 5 mg orally once a day (If on diuretic, the diuretic dose should be reduced).
Maintenance dose: 5 to 20 mg orally once a day.
Maintenance dose: 5 to 20 mg orally once a day.
Usual Adult Dose for Myocardial Infarction
Initial dose: 5 mg orally (within 24 hours of the onset of acute myocardial infarction).
Subsequent doses: 5 mg orally after 24 hours.
10 mg orally after 48 hours.
Maintenance dose: 10 mg orally once a day. Dosing should continue for six weeks.
Patients with a low systolic blood pressure (<=120 mm Hg) when treatment is started or during the first 3 days after the infarct should be given a lower 2.5 mg oral dose of lisinopril. If hypotension occurs (systolic blood pressure <=100 mm Hg) a daily maintenance dose of 5 mg may be given with temporary reductions to 2.5 mg if needed. If prolonged hypotension occurs (systolic blood pressure <90 mm Hg for more than 1 hour), lisinopril should be withdrawn.
Subsequent doses: 5 mg orally after 24 hours.
10 mg orally after 48 hours.
Maintenance dose: 10 mg orally once a day. Dosing should continue for six weeks.
Patients with a low systolic blood pressure (<=120 mm Hg) when treatment is started or during the first 3 days after the infarct should be given a lower 2.5 mg oral dose of lisinopril. If hypotension occurs (systolic blood pressure <=100 mm Hg) a daily maintenance dose of 5 mg may be given with temporary reductions to 2.5 mg if needed. If prolonged hypotension occurs (systolic blood pressure <90 mm Hg for more than 1 hour), lisinopril should be withdrawn.
Usual Adult Dose for Diabetic Nephropathy
Initial dose: 10 to 20 mg orally once a day.
Maintenance dose: 20 to 40 mg orally once a day.
Dosage may be titrated upward every 3 days.
Maintenance dose: 20 to 40 mg orally once a day.
Dosage may be titrated upward every 3 days.
Usual Geriatric Dose for Hypertension
Initial dose: 2.5 to 5 mg orally once a day.
Maintenance dose: Dosages should be increased at 2.5 to 5 mg/day increments at 1 to 2 week intervals.
Maximum dose: 40 mg/day.
Maintenance dose: Dosages should be increased at 2.5 to 5 mg/day increments at 1 to 2 week intervals.
Maximum dose: 40 mg/day.
Usual Pediatric Dose for Hypertension
Pediatric patients greater than or equal to 6 years of age:
Initial dose: 0.07 mg/kg once daily (up to 5 mg total)
Maintenance dose: Dosage should be adjusted according to blood pressure response.
Maximum dose: Doses above 0.61 mg have not been studied in pediatric patients.
Initial dose: 0.07 mg/kg once daily (up to 5 mg total)
Maintenance dose: Dosage should be adjusted according to blood pressure response.
Maximum dose: Doses above 0.61 mg have not been studied in pediatric patients.
Renal Dose Adjustments
CrCl 10 to 30 mL/min:
Initial dose: 5 mg orally once a day.
Dosage may be titrated upward until blood pressure is controlled or to a maximum total daily dose of 40 mg.
CrCl < 10 mL/min:
Initial dose: 2.5 mg orally once a day.
The dosage may be titrated upward until blood pressure is controlled or to a maximum of 40 mg/day.
Initial dose: 5 mg orally once a day.
Dosage may be titrated upward until blood pressure is controlled or to a maximum total daily dose of 40 mg.
CrCl < 10 mL/min:
Initial dose: 2.5 mg orally once a day.
The dosage may be titrated upward until blood pressure is controlled or to a maximum of 40 mg/day.
Liver Dose Adjustments
No adjustment recommended
