For every 1 L/min of oxygen by NC, you add 3% to the estimated FiO2. So someone on 4L NC is getting about 33% FiO2 (21 + 12). Of course the FiO2 when you are talking about nasal canula is always an estimate, as people are variable in how much they breathe through their mouth. The actual FiO2 can vary quite a bit.
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